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Additional info for Pharmacology of Conditioning, Learning and Retention. Proceedings of the Second International Pharmacological Meeting

Example text

L'expérimentateur doit être isolé par u n rideau ou mieux observer par un hublot, par l'intermédiaire de la télévision ou par l'enregistrement ciné­ matographique. Il serait souhaitable de faire des études aussi bien la nuit que le jour, mais l'observation dans l'obscurité totale nécessité l'utilisation de l'infra-rouge et de jumelles spéciales. Les études des psychophysiologistes sur le comportement d'exploration dans des boites (mazes) de formes variées (croix, H , Y) permettent de dé­ gager certaines notions, obtenues malheureusement la plupart du temps sur u n très petit nombre d'animaux.

The relation between fear and exploratory behaviour, J. Comp. Physiol. Psychol. 48, 132 — 6 (1955). NORTON, S. Behavioral patterns as a technique for studying psychotropic drugs. In Psychotropic Drugs, Elsevier, 73 — 82 (1957). 46 J . R. BOISSIER 45. I. The validity of defecation as a measure of emotionality in t h e rat, J. Genet. Psychol. 23, 7 5 - 8 7 (1940). 46. PATRICK, J . E . The effect of emotional stimuli on t h e activity level of the white rat, J. Comp. Psychol. 12, 3 5 7 - 6 4 (1931).

Quoi qu'il en soit, l'utilisation des modifications du comportement de l'Animal en situation libre apparaît comme une méthode précieuse d'étude 42 J . R. BOISSIER des substances psychotropes. Cette méthode ne pourra jamais constituer une technique de screening, en raison de sa difficulté. Elle ne devra pas être isolée des autres groupes de méthodes et ne constituer qu'un des procédés d'investigation.

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