Download e-book for iPad: High-Yield Pharmacology (3rd Edition) (High-Yield Series) by Stephanie T. Weiss
By Stephanie T. Weiss
ISBN-10: 0781792738
ISBN-13: 9780781792738
Now in its 3rd variation, High-Yield™ Pharmacology presents a succinct evaluate of pharmacology whereas clarifying tough suggestions. Need-to-know info is gifted in a transparent, concise define structure. extra positive aspects comprise up to date drug references, a drug index, key issues in daring, and tables summarizing key proof. no matter if a scholar is reviewing for the end-of-year checks in pharmacology or brushing up for the USMLE, this e-book presents a short evaluation of this not easy subject.
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Now in its 3rd version, High-Yield™ Pharmacology presents a succinct evaluation of pharmacology whereas clarifying tricky strategies. Need-to-know details is gifted in a transparent, concise define layout. extra positive aspects comprise up to date drug references, a drug index, key issues in daring, and tables summarizing key evidence.
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Example text
Reduced effects on the CNS 5. Respiratory depression. These drugs reduce the sensitivity of the medullary respiratory centers to CO2. a. Respiratory depression is increased when these drugs are combined with any other sedating drug. b. This is the cause of death from an overdose. c. Tolerance does not develop to the depressant action on respiration. d. Respiratory depression is very marked with barbiturates and very weak with benzodiazepines. 6. Abuse potential. Physical dependence occurs with all these drugs and results in an abstinence syndrome upon withdrawal.
Vasodilation of renal and mesenteric blood vessels due to stimulation of D receptors, making it useful for treating shock E. The effects, uses, and side effects for the various sympathomimetics are summarized in Table 2–5. VIII α-Adrenoceptor Antagonists A. Drugs in this class inhibit α-adrenoceptors, thereby reducing the α-effects of endogenously released NE. B. NONSELECTIVE antagonists block both α1- and α2-adrenoceptors. 1. The properties of the various α-antagonists are quite different. a. Phenoxybenzamine (Dibenzyline) is an alkylating agent that forms a reactive intermediate.
1. They have bulky alkyl substitutions on the nitrogen and an oxymethylene bridge near the aromatic ring. 2. The l-isomers are the active forms. C. THE NONSELECTIVE β-blockers inhibit both β1- and β2-adrenoceptors. 1. Propranolol (Inderal) is 90% bound to plasma proteins and is rapidly metabolized by the liver. a. 3) due to first-pass metabolism. b. The IV dose is one third of the oral dose. c. The half-life is short, approximately 3 hours. d. An active metabolite, hydroxypropranolol, is formed.
High-Yield Pharmacology (3rd Edition) (High-Yield Series) by Stephanie T. Weiss
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