Toxicological profiles - Formaldehyde by Jeffrey P. Koplan PDF

Pharmacology

By Jeffrey P. Koplan

ISBN-10: 0756707528

ISBN-13: 9780756707521

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1997). 4 to 3 ppm can produce symptoms of mild to moderate irritation of the eyes, nose, and throat. The odor threshold for formaldehyde in humans has been reported to be 1 ppm (Leonardos et al. 05 ppm (ACGIH 1992). Descriptions follow of findings for irritation of the eyes, nose, and throat from a sampling of available controlled exposure studies of acute irritation, emphasizing studies that examined symptoms of irritation at the lower end of this concentration range (Andersen and Molhave 1983; Bender et al.

2 ppm formaldehyde, 6 hours/day, 5 days/week for up to 588 days (Albert et al. 3 ppm (but not 2 ppm), 6 hours/day, 5 days/week for up to 24 months (Kerns et al. 1983b; Swenberg et al. 7, 2, 6, or 10 ppm) 6 hours/day, 5 days/week for 24 months (Monticello et al. 3 or 2 ppm), 6 hours/day, 5 days/week for up to 28 months (Kamata et al. 1997). In general, observations of increased mortality in the rat bioassays occurred after about one year of exposure and were associated with the development of nasal squamous cell carcinomas.

1986; Witek et al. 1986), 15 formaldehyde-exposed laboratory workers exposed to 0 or 2 ppm for 40 minutes with or without exercise (Schachter et al. 1987), 15 asthmatic volunteers exposed to 0 or 2 ppm for 40 minutes with or without exercise (Witek et al. 1986, 1987), 18 subjects, 9 of whom had complaints of health effects from exposure to urea-formaldehyde foam insulation in their homes, exposed to 1 ppm for 90 minutes (Day et al. 4 ppm for 2 hours (Gorski et al. 4 ppm for 2 hours (Krakowiak et al.

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Toxicological profiles - Formaldehyde by Jeffrey P. Koplan


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