Pharmacology of Ganglionic Transmission - download pdf or read online


By D. A. Kharkevich (auth.), Professor Dr. Dimitry A. Kharkevich (eds.)

ISBN-10: 364267397X

ISBN-13: 9783642673979

ISBN-10: 3642673996

ISBN-13: 9783642673993

D.A. KHARKEVICH The heritage of the research of ganglionic components starts off with the paper of LANGLEY and DICKINSON (1889), who verified the facility of nicotine to dam the neurones within the more advantageous cervical ganglion. This was once a substantial discovery because the authors ascertained that impulses have been transmitted from pre- to postganglionic neurones within the autonomic ganglia. at the same time they indicated the potential of pharmaco­ logical impact upon interneuronal transmission in autonomic ganglia. the belief of ganglionic receptors in particular delicate to nicotine logically. Later, LANGLEY (1905, 1906) thought of the matter of receptors with appreciate to neuro-effector synapses. it really is amazing that he was once one of many first to place ahead the idea of chemical mediation of excitation (" ... the worried impulse are usually not go from nerve to muscle by means of an electrical discharge, yet via the secretion of a unique substance on the finish of the nerve": LANGLEY, 1906, p. 183). moreover, LANGLEY JOHN N. LANGLEY (1852-1926) D.A. KHARKEVICH 2 and his collaborators controlled to outline the topography of autonomic ganglia extra accurately through nicotine. it may be pointed out that it was once he who brought the phrases "autonomic worried approach" and "parasympathetic fearful system".

Show description

Read or Download Pharmacology of Ganglionic Transmission PDF

Similar pharmacology books

Download e-book for kindle: High-Yield Pharmacology (3rd Edition) (High-Yield Series) by Stephanie T. Weiss

Now in its 3rd variation, High-Yield™ Pharmacology presents a succinct assessment of pharmacology whereas clarifying tricky ideas. Need-to-know info is gifted in a transparent, concise define layout. extra positive factors contain up to date drug references, a drug index, key issues in daring, and tables summarizing key evidence.

Get In Silico Methods for Predicting Drug Toxicity PDF

This designated quantity explores in silico tools for pharmaceutical toxicity by means of combining the theoretical complicated examine with the sensible software of the instruments. starting with a piece masking refined types addressing the binding to receptors, pharmacokinetics and adsorption, metabolism, distribution, and excretion, the e-book keeps with chapters delving into versions for particular toxicological and ecotoxicological endpoints, in addition to wide perspectives of the most projects and new views with the intention to in all likelihood increase our method of modelling prescription drugs.

Additional resources for Pharmacology of Ganglionic Transmission

Sample text

No IPSPs are observed during a decrease in the activity of the neurones of the ganglion caused by the afferent stimulation. Thus this decrease is due to an inhibition that has occurred in the central nervous system but not in the ganglion. C. Summary The main function of the extramural autonomic ganglion is distribution of the excitation that comes from the central nervous system through the relatively small number of preganglionic fibres among the much more numerous postganglionic fibres. In some groups of neurones of amphibian and avian ganglia this is attained by means of a simple schema by which a single preganglionic fibre fires many efferent neurones of the ganglion.

Pp. 76-90. : Growth control of nerve cells by a protein factor and its antiserum. : Nerve growth factor. Physiol. Rev. : Long latent periods and further analysis of slow synaptic responses in sympathetic ganglia. 1. Neurophysiol. : Generation of slow inhibitory and excitatory postsynaptic potentials. Fed. Proc. : Adrenergic mediation of slow inhibitory postsynaptic potential in sympathetic ganglia of the frog. J. Neurophysiol. : Concomitant changes in formaldehyde-induced fluorescence of dopamine interneurons and in slow inhibitory postsynaptic potentials of the rabbit superior cervical ganglion, induced by stimulation of the preganglionic nerve or by a muscarinic agent.

The onset and development of transmission in the chick ciliary ganglion. J. Physiol. : Synapse formation during embryogenesis of ganglion cells lacking a periphery. J. Physiol. : Synaptic transmission and cell death during normal ganglionic development. J. Physiol. : Properties of sympathetic B ganglion cells. J. Cell. Compo Physiol. : Potential changes evoked in a curarized sympathetic ganglion by presynaptic volleys of impulses. J. Cell. Compo Physiol. : Morphology of antagonist innervation in the nervous system.

Download PDF sample

Pharmacology of Ganglionic Transmission by D. A. Kharkevich (auth.), Professor Dr. Dimitry A. Kharkevich (eds.)

by Christopher

Rated 4.77 of 5 – based on 22 votes