Optimizing the ''Drug-Like'' Properties of Leads in Drug by Ronald T. Borchardt, Edward H. Kerns, Michael J. Hageman, PDF
By Ronald T. Borchardt, Edward H. Kerns, Michael J. Hageman, Dhrien R. Thakker, James L. Stevens
ISBN-10: 0387340564
ISBN-13: 9780387340562
ISBN-10: 0387449612
ISBN-13: 9780387449616
This publication arises from a workshop prepared by means of the yankee organization of Pharmaceutical Scientists entitled "Optimizing the Drug-Like houses of Leads in Drug Discovery," which happened in Parsippany, NJ in September 2004. The workshop concerned with the optimization of the drug-like houses of leads in drug discovery. the amount outlines recommendations and methodologies designed to lead pharmaceutical and biotechnology businesses in the course of the drug discovery and improvement strategy.
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Additional resources for Optimizing the ''Drug-Like'' Properties of Leads in Drug Discovery
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Sparreboom A, van Asperen J, Mayer U, Schinkel AH, Smit JW, Meijer DK, Borst P, Nooijen WJ, Beijnen JH, and van Tellingen O. Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine. Proc Natl Acad Sci U S A 1997; 94:2031-2035. Speeg KV, Maldonado AL, Liaci J, and Muirhead D. Effect of cyclosporine on colchicine secretion by a liver canalicular transporter studied in vivo. Hepatology 1992; 15:899-903. Thiebaut F, Tsuruo T, Hamada H, Gottesman MM, Pastan I, and Willingham MC.
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Optimizing the ''Drug-Like'' Properties of Leads in Drug Discovery by Ronald T. Borchardt, Edward H. Kerns, Michael J. Hageman, Dhrien R. Thakker, James L. Stevens
by Ronald
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