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By Dawn B. Willis (auth.), Gholamreza Darai (eds.)
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Additional resources for Molecular Biology of Iridoviruses
This preliminary analysis revealed that unlike FV3 (130) and FLDV (132) DNAs, TIV DNA does not contain methylated CpG sequences. These results agree favorably with those of Thomas (133) which indicated that no methycytosine or 5'-hydroxymethylcytosine residues were present in TIV DNA. Therefore, methylation may not contribute much to TIV genomic size variation. It would be of immediate interest to obtain genomic size estimates of a plaque pure TIV from a homogeneous tissue culture system when it is available.
Albopictus cell line occurring late in infection, likely just prior to the assembly of progeny virions. The use of viral mutants to study the effects of specific lesions in the viral replication cycle has been well documented in the literature (63, 64, 89). Probably the best studied semipermissive cell system is the infection of African green monkey kidney cells with human adenovirus type 2 (Ad2; 90). Replication of human adenoviruses is often incomplete in most cultured cells of nonhuman origin.
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Molecular Biology of Iridoviruses by Dawn B. Willis (auth.), Gholamreza Darai (eds.)