Get Dictyostelids: Evolution, Genomics and Cell Biology PDF


By Sandra Muñoz-Braceras, Ana Mesquita, Ricardo Escalante (auth.), Maria Romeralo, Sandra Baldauf, Ricardo Escalante (eds.)

ISBN-10: 3642384862

ISBN-13: 9783642384868

ISBN-10: 3642384870

ISBN-13: 9783642384875

Since their discovery in 1869, the dictyostelids have attracted the eye of scientists in a wide selection of fields. This curiosity has stemmed from their abnormal way of life and developmental houses, that have been formed by means of the evolutionary forces that generated multicellularity in the course of eukaryotic evolution. extra lately, the dictyostelids have won recognition as a result notable similarities discovered on the genomic, mobile and biochemical degrees with human cells, which has propelled the species Dictyostelium discoideum to turn into a version method for biology and medication in lots of laboratories. This e-book covers the newest advances in our wisdom of those outstanding organisms with issues spanning from their evolutionary heritage, ecology and variety to the new discoveries relating to their mobile and molecular biology.

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1000117 De Lozanne A, Spudich JA (1987) Disruption of the Dictyostelium myosin heavy chain gene by homologous recombination. Science 236:1086–1091 Debray FG, Lambert M, Mitchell GA (2008) Disorders of mitochondrial function. Curr Opin Pediatr 20(4):471–482. 0b013e328306ebb6 Depraitere C, Darmon M (1978) Croissance de l’amibe sociale Dictyostelium discoideum sur differentes especes bacteriennes. Ann Microbiol (Inst Pasteur) 129B:451–461 DiMauro S, Schon EA (2008) Mitochondrial disorders in the nervous system.

Proc Natl Acad Sci USA 79:7356–7360 Hoeller O, Kay RR (2007) Chemotaxis in the absence of PIP3 gradients. Curr Biol 17(9):813–817 Hori H, Osawa S, Iwabuchi M (1980) The nucleotide sequence of 5S rRNA from a cellular slime mold Dictyostelium discoideum. Nucl Acids Res 8:5535–5539 Inoue Y, Klionsky DJ (2010) Regulation of macroautophagy in Saccharomyces cerevisiae. Semin Cell Dev Biol 21(7):664–670. 009 S1084-9521(10)00071-6 [pii] Iwashkiw JA, Seper A, Weber BS, Scott NE, Vinogradov E, Stratilo C, Reiz B, Cordwell SJ, Whittal R, Schild S, Feldman MF (2012) Identification of a general O-linked protein glycosylation system in Acinetobacter baumannii and its role in virulence and biofilm formation.

This conservative tendency is still stronger for proteins of unknown function. Some of these proteins are highly conserved among evolutionarily distant species suggesting that they play relevant roles, perhaps related to human diseases. The inherent difficulty in the study of a disease-related protein of unknown function or the complexity of signaling networks in pathology can be partially overcome by the powerful genetics of simple models, as illustrated in this review. These models may serve to give us new and unexpected insights.

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Dictyostelids: Evolution, Genomics and Cell Biology by Sandra Muñoz-Braceras, Ana Mesquita, Ricardo Escalante (auth.), Maria Romeralo, Sandra Baldauf, Ricardo Escalante (eds.)

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