Download e-book for iPad: Chirality in Drug Design and Synthesis by C. Brown
By C. Brown
ISBN-10: 0121366707
ISBN-13: 9780121366704
This can be a textual content which offers with the valuables of left-handed and right-handed structural shape in chemical substances utilized in drug layout and drug synthesis. The booklet covers pharmacological, clinical, natural chemical and toxicological purposes
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Extra resources for Chirality in Drug Design and Synthesis
Example text
Clin. Pharmacokinet. 9, 371-373. Jenner, P. and Testa, B. (1973). The influence of sterochemical factors on drug disposition. Drug Metabol. Rev. 2, 117-184. Kidwell, G. , Lima, J. J. Schaal, S. F. andMuir, W. M. (1989). Hemodynamic and electrophysiologic effects of disopramide enantiomers in a canine blood superfusion model. /. Cardiovasc. Pharmacol. 13, 644-655. Kroemer, H. , Parker, R. A. and Roden, D. M. (1989a). Flecainide enantiomers: disposition in human subjects and electrophysiologic actions in vitro.
Pharmacol. Sei. 73, 1671-1673. , Low, L. , Trager, W. , O'Reilly, R. , Motley, C. H. and Goulart, D. A. (1986). The warfarin-sulfinpyrazone interaction: stereochemical considerations. Clin. Pharmacol. Ther. 39, 15-24. , Hopkins, K. , Garstang, F. M. and Rowland, M. (1987). Comparative effects of ranitidine and cimetidine on the pharmacokinetics and pharmacodynamics of warfarin in man. Eur. J. Clin. Pharmacol. 32, 165-172. Tucker, G. T. and Lennard, M. S. (1990). Enantiomer specific pharmacokinetics.
And Testa, B. (1973). The influence of sterochemical factors on drug disposition. Drug Metabol. Rev. 2, 117-184. Kidwell, G. , Lima, J. J. Schaal, S. F. andMuir, W. M. (1989). Hemodynamic and electrophysiologic effects of disopramide enantiomers in a canine blood superfusion model. /. Cardiovasc. Pharmacol. 13, 644-655. Kroemer, H. , Parker, R. A. and Roden, D. M. (1989a). Flecainide enantiomers: disposition in human subjects and electrophysiologic actions in vitro. Clin. Pharmacol. Ther. 46, 584-590.
Chirality in Drug Design and Synthesis by C. Brown
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