Reelin Glycoprotein: Structure, Biology and Roles in Health by Cheng-Chiu Huang, Gabriella D’Arcangelo (auth.), S. Hossein PDF

Biology

By Cheng-Chiu Huang, Gabriella D’Arcangelo (auth.), S. Hossein Fatemi M.D., Ph.D. (eds.)

ISBN-10: 0387767606

ISBN-13: 9780387767604

Reelin glycoprotein is a huge secretory protein with very important roles in embryogenesis and through grownup lifestyles. Reelin gene mutations or deficiency of the protein product reason irregular cortical improvement and reelin signaling impairment in mind. because the first discovery of the reelin mutant mouse in 1951 by way of Falconer, and later discovery of the gene for reelin in 1995, there was an explosion of recent wisdom approximately this significant molecule. Reelin Glycoprotein: constitution, Biology and Roles in future health and Disease, written by way of a global panel of specialists, summarizes the nation of the data on quite a few facets of reelin. subject matters contain the reelin gene and its receptors, downstream effector molecules in reelin signaling cascade, chemistry and constitution of reelin, comparative anatomy of reelin, presence of reelin in quite a few physique tissues, reelin mutations, and abnormalities of reelin construction in neuropsychiatric problems and melanoma. This publication will function a origin for research of this rising novel protein for all neuroscientists and clinicians.

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R. van Furth (auth.), Ralph van Furth (eds.)'s Mononuclear Phagocytes: Biology of Monocytes and Macrophages PDF

Biology

By R. van Furth (auth.), Ralph van Furth (eds.)

ISBN-10: 9048141710

ISBN-13: 9789048141715

ISBN-10: 9401580707

ISBN-13: 9789401580700

Mononuclear phagocytes, which come with macrophages, monocytes and their precursor cells, are crucial cells within the host defence opposed to micro-organisms and tumor cells.
over the past twenty-five years study at the biology of mononuclear phagocytes has elevated greatly. This stimulated Professor R. van Furth to arrange 5 overseas meetings in this topic in Leiden, the Netherlands. The edited lawsuits of those meethings have been released: in 1970 Mononuclear Phagocytes; in 1975 Mononuclear Phagocytes in Immunity, Infections and Pathology; in 1980 Mononuclear Phagocytes -- useful Aspects; and in 1985 Mononuclear Phagocytes -- features, body structure and Function. experiences of those volumes, released in foreign journals, praised them because the newest cutting-edge courses. The booklet of 1991 comprises 88 chapters written through greater than 2 hundred authors.

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Fiona Giles's Fresh Milk: The Secret Life of Breasts PDF

Biology

By Fiona Giles

ISBN-10: 1741767555

ISBN-13: 9781741767551

The commonly acclaimed writer of Dick for an afternoon showcases her razor-sharp knack for tart and provocative remark during this special compendium of reports, thoughts, and reportage at the age-old perform of breastfeeding.

numerous courses to breastfeeding crowd the bookshelves nowadays; now not one in every of them speaks to girls with whatever coming near near writer Fiona Giles's point of intimacy and energy. Alternately informative, affecting, and without warning erotic, this actually exceptional paintings from the bestselling writer of Chick for an afternoon and Dick for an afternoon can pay late homage to the miracle of the lactating breast-a phenomenon not often explored outdoors of academic literature and parenting magazines.

thank you mostly to risque advertisements and the gravity-defying cleavage sported through our most well-liked celebs, uncovered breasts (real or faux) now not carry any secret. yet when they shift into milk-bearing mode, breasts abruptly disappear from the general public eye. In clean Milk, via a various number of tales, thoughts, and private money owed, Giles uncovers the myths, truths, and social and mental implications of breastfeeding.

From the more youthful mom grappling with the bewildering trappings of maternity put on, to the lady who reveals herself apparently aroused by means of new sensations, to the fashionable dad who learns the bits and bobs of breastfeeding, the photographs in Giles' eye-opening publication provide a welcome substitute to rote how-to tutorials and impersonal step by step publications. by means of turns poignant and informative, horny and witty, empathic and empowering, clean Milk offers every thing we needed to understand approximately breastfeeding that our moms by no means informed us.

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Download e-book for kindle: Electron Microscopy: Methods and Protocols by John J. Bozzola (auth.), John Kuo (eds.)

Biology

By John J. Bozzola (auth.), John Kuo (eds.)

ISBN-10: 1588295737

ISBN-13: 9781588295736

ISBN-10: 1597452947

ISBN-13: 9781597452946

The revised and elevated moment version of this publication offers the most recent know-how in electron microscopy, whereas conserving the practicality and accessibility of the acclaimed first version. just like the first version, this quantity offers transparent, concise directions on processing organic specimens and contains dialogue at the underlying rules of nearly all of the techniques awarded. Electron Microscopy includes significant parts of electron microscopy-transmission electron microscopy (TEM) and scanning electron microscopy (SEM). The TEM region covers a number of key options, together with: traditional specimen education tools for aesthetic cells and biomedical and plant tissues; cryospecimen guidance through high-pressure freezing and cryoultramicrotomy adverse staining and immunogold labeling concepts; and TEM crystallography and cryo-TEM tomography. The SEM zone equally attends to conventional-, variable pressure-, environmental-, and cryoscanning microscopy strategies, in addition to the applying of X-ray microanalysis. Protocols for the appliance of X-ray microanalysis to SEM and mass spectrometry finish the volume.

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Read e-book online Lifelines - Biology Beyond Determinism [poor layout PDF

Biology

By Steven Rose

ISBN-10: 0195120353

ISBN-13: 9780195120356

Reductionism--understanding advanced strategies via breaking them into less complicated elements--dominates medical pondering all over the world and has definitely proved a robust instrument, resulting in significant discoveries in each box of technology. yet reductionism should be taken too a long way, specially within the lifestyles sciences, the place sociobiological considering has bordered on organic determinism. therefore renowned technological know-how writers equivalent to Richard Dawkins, writer of the hugely influential The egocentric Gene, can write that humans are only "robot autos blindly programmed to maintain the egocentric molecules referred to as genes." certainly, for lots of in technological know-how, genes became the elemental unit for realizing human life: genes be certain each element of our lives, from own luck to existential melancholy: genes for healthiness and ailment, genes for illegal activity, violence, and sexual orientation. Others might say that this is often reductionism with a vengeance.
In Lifelines, biologist Steven Rose deals a robust replacement to the ultradarwinist claims of Dawkins, E.O. Wilson, Daniel Dennett and others. Rose argues opposed to an severe reductionist method that may make the gene the major to figuring out human nature, in desire of a extra advanced and richer imaginative and prescient of existence. He urges in its place that we specialize in the organism and particularly at the organism's lifeline: the trajectory it takes via time and area. Our own lifeline, Rose issues out, is unique--even exact twins, with exact genes at start, will vary over the years. those variations are patently now not embedded in our genes, yet turn up via our developmental trajectory within which genes, as a part of the biochemical orchestra of trillions of cells in every one human physique, have a big part--but just a part--to play. to demonstrate this concept, Rose examines fresh study in smooth biology, and particularly disciplines--genetics (which seems to be on the influence of genes on shape) and developmental biology (which examines the interplay among the organism and the environment)--and he explores new principles on organic complexity proposed by means of scientists resembling Stuart Kauffman. He exhibits how our lifelines are developed throughout the interaction of actual forces--such because the intrinsic chemistry of lipids and proteins, and the self-organizing and stabilizing houses of advanced metabolic webs--and he reaches a startling end: that organisms are lively gamers of their personal destiny, no longer easily the playthings of the gods, nature, or the inevitable workings out of gene-driven average choice. The organism is either the weaver and the trend it weaves.
Lifelines might be a rallying aspect for all who search a substitute for the at the moment trendy, deeply determinist bills which dominate well known technological know-how writing and, actually, crowd the pages of a few of the foremost clinical journals. in keeping with good, cutting-edge learn, it not just makes vital contributions to our knowing of Darwin and usual choice, yet will swing the pendulum again to a richer, extra advanced view of human nature and of existence.

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Frank Hippel (ed.)'s Tinbergen's Legacy in Behaviour: Sixty Years of Landmark PDF

Biology

By Frank Hippel (ed.)

ISBN-10: 9004170294

ISBN-13: 9789004170292

ISBN-10: 9004180427

ISBN-13: 9789004180420

This e-book lines very important medical advances in ethology, evolutionary biology, ecology, ecotoxicology and developmental genetics made attainable throughout the stickleback version through a range of key papers released within the first 60 years of 'Behaviour' besides observation and retrospective essays.

In a flurry of post-war productiveness, Niko Tinbergen re-established his lab in Leiden, wrote landmark papers and his recognized e-book 'The examine of Instinct', and based the magazine 'Behaviour' to serve the burgeoning box of ethology. Tinbergen and his senior assistant, Jan van Iersel, released their vintage paper, "Displacement reactions within the three-spined stickleback," within the first factor of his new magazine in 1948. Stickleback at the moment are a robust version within the fields of behavioural ecology, evolutionary biology, developmental genetics, and ecotoxicology - a unprecedented improvement for a small fish that begun its modeling profession between an enthusiastic center of Tinbergen scholars within the Thirties. From a chain of smart experiments with painted version fish to using the sequenced genome to investigate the genetic foundation of courtship, stickleback technology improved in leaps and boundaries, frequently through seminal reports released within the pages of 'Behaviour'.

'Tinbergen’s Legacy in Behaviour' strains sixty years within the improvement of technology utilizing stickleback as a version, with 34 unique articles masking themes starting from homosexuality and cannibalism to genetics and speciation. Desmond Morris, Theo Bakker, Robert Wootton, Michael Bell, Tom Reimchen, Boyd Kynard, Harman Peeke, and Iain Barber offer clean retrospectives on their republished works. observation via Frank von Hippel accompanies the articles and explains the jobs they performed within the frontiers of technology as researchers falsified or improved upon one another’s principles.

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Sunghoon Kim's Aminoacyl-tRNA Synthetases in Biology and Medicine PDF

Biology

By Sunghoon Kim

ISBN-10: 940178700X

ISBN-13: 9789401787000

ISBN-10: 9401787018

ISBN-13: 9789401787017

This ebook will specialize in new molecular interactions and novel actions and the linked ailments which were lately came across from the experiences of eukaryotic and mammalian aminoacyl-tRNA synthetases. moreover, the capability purposes of ARS researches in biotechnology and medication could be addressed.

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