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By Lawrence Kruger, Barbara E. Rodin (auth.), Ralph L. Kitchell, Howard H. Erickson (eds.)

ISBN-10: 1461475627

ISBN-13: 9781461475620

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7. Schematic illustration of some synaptic mechanisms and transmitters known or postulated to modify activity of multireceptive and nocireceptive dorsal horn neurons. [FromM. Zimmermann (27), Advances in Pain Research and Therapy. ) experiments, establishing that the sensitivity of an animal to noxious stimulation can be dramatically reduced by electrical stimulation of discrete regions of the brain stem (14). Neurophysiological studies suggest that an endogenous analgesic system exists, which at least partly operates on dorsal horn neurons via tryptaminergic pathways.

Randt. Relation of peripheral nerve fiber size and sensation in man. Arch. Neural. Psychiatry 3: 381-385, 1960. Cunningham, F. , and M. J. T. Fitzgerald. ]. Anat. 112: 93-97, 1972. , and W. Janig. Activation of myelinated afferents ending in a neuroma by stimulation of the sympathetic supply in the rat. Neurosci. Lett. 24: 43-47, 1981. , D. Schonfeld, Z. Seltzer, and P. D. Wall. Two modes of cutaneous reinnervation following peripheral nerve injury. ]. Comp. Neural. 185: 211-220, 1979. 22 Kruger and Rodin 32.

46. Henry, J. L. Effects of substance P on functionally identified units in the cat spinal cord. Brain Res. 114: 439-451, 1976. 47. Hensel. , K. H. Andres, and M. von During. Structure and function of cold receptors. Pfluegers Arch. 352: 1-10, 1974. 48. , J. 0. Kellerth, G. Nilsson, and B. Pernow. Substance P: localization in the central nervous system and in some primary sensory neurons. Science 190: 889-890, 1975. 49. , R. Jurna, R. Gamse, and F. Lembeck. Nociceptive threshold after neonatal capsaicin treatment.

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Animal Pain: Perception and Alleviation by Lawrence Kruger, Barbara E. Rodin (auth.), Ralph L. Kitchell, Howard H. Erickson (eds.)

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