Read e-book online Advances in Drug Research, Vol. 26 PDF

Pharmacology

By Bernard Testa, Urs A. Meyer (Eds.)

ISBN-10: 0120133261

ISBN-13: 9780120133260

Quantity 26 maintains the fad of shorter, extra widespread volumes. With quantity 25, the sequence received a brand new co-editor, Urs Meyer. whereas keeping the dedication to post chapters on healing or chemical periods and on basic themes or strategies, the sequence' insurance has multiplied to incorporate methodological chapters, and new components of well-known or capability value to drug learn, specially in molecular pharmacology.

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Additional info for Advances in Drug Research, Vol. 26

Example text

In Table 1 we compare some characteristics and attributes of bulk water and the molecule of H20. 2 The Soluble State The conventional approach to the understanding of chemical events is to model a system with the reagents (reactants) as isolated participants. On occasion, recognition is made of the presence of a dimer or a hydrate as a functioning member of a chemical interaction (reaction). But these are exceptions. g. water in a biological reaction) is usually neglected because it is poorly understood (Testa, 1984).

Estabrook, R. , Gonzales, F. , Coon, M. , Gunsalus, I. , Okuda, K. and Nebert, D. W. (1993). DNA Cell Biol. 12, 1-51. COMPLEXITY AND EMERGENCE IN DRUG RESEARCH 41 Pastor, R. , Venable, R. M. and Karplus, M. (1991). Proc. Natl Acad. Sci. USA 88, 892-896. Pavlic, M. R. (1987). Arch. Biochem. Biophys. 253, 446-452. Pullman, B. (1989). In "Advances in Drug Research", Vol. 18 (B. ), pp. 1-113. Academic Press, London. Quiocho, F. , Wilson, D. K. and Vyas, N. K. (1989). Nature 340, 404-408. Rabitz, H.

D. (1988). J. Am. Chem. Soc. 110, 5959-5967. Devaux, P. F. (1991). Biochemistry 30, 1163-1173. Dill, K. A. (1990). Biochemistry 29, 7133-7155. Eigen, M. (1990). Curr. ~Life Sci. 33(6), 16-17. Eigen, M. (1994). Biophys. Chem. 50, 1. Eisenberg, H. (1990). Eur. J. Biochem. 187, 7-22. , Mark, A. , Brunne, R. , Testa, B. and van Gunsteren, W. F. (1993). J. Med. Chem. 36, 3757-3764. , Roberts, G. C. K. and Burgen, A. S. V. (1974). In "Molecular and Quantum Pharmacology" (E. Bergmann and B. Pullman, eds), pp.

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Advances in Drug Research, Vol. 26 by Bernard Testa, Urs A. Meyer (Eds.)


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